Production of Bioactive Natural Products from Marine Microorganisms

Paper ID : 1054-ISCH

Authors

Mohamed Saleh Abdelfattah * Ain Helwan

Abstract

The marine environment contains many microorganisms living in extreme conditions such as high salinity, temperature, and pressure. These microorganisms were reported to produce unique and structurally novel natural organic compounds allowing their survival in such conditions. Among such microorganisms, Gram-positive actinomycetes bacteria are of special importance. They produce secondary metabolites with a wide range of biological activities, including antimicrobial and antitumor activities. In Egypt, the Mediterranean and Red Seas are rich with microorganisms and provide a unique opportunity to explore bioactive compounds. Our research group is dedicated to investigating these microorganisms, focusing on their potential to produce novel bioactive compounds that could lead to innovative applications in medicine and biotechnology. We have identified several new natural products with promising chemical structures and biological activities, like antimicrobial and anticancer activities. These discoveries not only enhance our understanding of marine biodiversity but also pave the way for the development of new therapeutic agents.

Keywords

Marine natural products, NMR, antimicrobial, anticancer

Status: Abstract Accepted (Oral Presentation)