| Response of certain Fungal isolates to gamma radiation |
| Paper ID : 1048-ISCH |
| Authors |
|
Reem Mohsen Mahmoud * demonstrator at botany and microbiology department , faculty of science ,Helwan university |
| Abstract |
| Fungal growth, spore germination, and metabolic activity are all significantly inhibited by gamma radiation, a type of ionizing energy. Higher doses result in severe cellular damage through DNA strand breakage, protein denaturation, and breakdown of cell membrane integrity, leading to full fungal inactivation. Low doses may only slow growth or stimulate it as a stress response. Due to the radioprotective qualities of melanin, melanin-pigmented fungi have improved survival capabilities, however there is notable variance in radio-tolerance among species. Additionally, sub-lethal dosages have the ability to upregulate particular metabolic pathways and cause cryptic growth, which may increase the synthesis of secondary metabolites. This study methodically studied the impact of increasing gamma radiation doses (0.5 to 10 kGy) on 5 fungal isolates' in vitro growth. . Radial growth was measured daily over six days, and growth rates were calculated. Results demonstrate a clear, dose-dependent inhibitory effect. There was variation in radiosensitivity among isolates. Growth rates were severely reduced, with high doses (5–10 kGy) leading to stasis or death in sensitive isolates. |
| Keywords |
| Gamma radiation , growth rate ,radioprotective ,pigmented fungi |
| Status: Abstract Accepted (Poster Presentation) |